Our Services
Knowchem operates as a full-spectrum Contract Development and Manufacturing Organization (CDMO), offering advanced capabilities in chemical synthesis, process development, and small-scale manufacturing.

Research & Innovation
Our research team brings together expertise in synthesis chemistry and chemical engineering to address complex challenges in process chemistry. We operate with precision and depth, enabling us to support investigational-stage programs across a broad spectrum of chemical domains.
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Core Capabilities:
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High Temperature reactions (up to 450 Degrees), Purifications using High Vacuum Distillations
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Handling of hazardous reactions including bromination, chlorination, sulfonation, and hydrogenation
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Advanced purification using fractionation columns with 100 theoretical plates
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Analytical method development, validation, and transfer
Process Development
We specialize in the design, optimization, and scale-up of robust chemical processes with a strong emphasis on operational efficiency and environmental stewardship. Our approach is rooted in analytical thinking and decades of hands-on experience.
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Development Services Include:
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Comprehensive process development and optimization
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Custom synthesis at gram to kilogram scale
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Technology development and transfer for APIs and key intermediates
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Process troubleshooting to enhance cost-efficiency and sustainability
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Integration of effluent treatment strategies into development workflows


Manufacturing Support
Knowchem offers a unique model wherein process demonstrations can be executed in-house at plant scale, facilitating seamless technology transfer. We deliver reliable, small-scale production and support contract manufacturing of developed products.
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Manufacturing Capabilities:
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Production from gram-scale to hundreds of kilograms per batch
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Plant-scale process demonstration and equipment advisory
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Contract manufacturing services aligned with developed processes
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End-to-end support for transfer and implementation at client facilities
Molecules We've Developed















